Compound Classes
solid Phase Peptide Synthesis

Solid phase Peptide Synthesis

All products available against order or for contract manufacture
Orange : Introduced by Bharavi Labs
Green   : Available ex-stock or at short notice
 
Name : Wang resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Peptide synthesis by Fmoc strategy
Cleavage : 50% TFA-DCM
 
 
Name : Wang chloride resin
Technical Information
1% 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Solid phase organic synthesis
Cleavage : TFA-DCM
 
 
Name : Wang chloride resin
Technical Information
1% 100-200 or 200-400 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Solid phase organic synthesis
Cleavage : TFA-DCM
 
 
Name : Brominated Wang resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Photolabile linker for library generation
Cleavage: Exposure to UV light
References : S. Wang, JOC, 1976, 41, 3256
 
Name : Brominated PPOA resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage:Peptide synthesis by Boc strategy
Cleavage : Strong acids like HF
References : A. R. Mitchell, et al. JOC, 1978, 43, 2845
 
Name : 3-Methoxy Wang resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : SPOS
Cleavage : Acid sensitive
References : M. Mergler etal, TL, 1998, 29, 4009
 
Name : Barlos (2-Chlorotrityl chloride) resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Use : Popular peptide synthesis resin esp. proline & cysteine
Cleavage : CHCl3:EtOH:AOAc
See also amino acids linked to 2-chlorotrityl resin
 
Name : Merrifield Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
Loading : ~1.2 mmol/g; also offered : 0.6; 2.4; 3.6 mmol/g
Usage : Extensively used core resin for solid phase peptide synthesis and as core resin for other resins
 
Name : PAM alcohol
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage:Peptide synthesis by Boc strategy
Cleavage : Strong acids like HF
References : A. R. Mitchell, et al. JOC, 1978, 43, 2845
 
Name : PAM bromide
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage:Peptide synthesis by Boc strategy
Cleavage : Strong acids like HF
References : A.R. Mitchell etal, JOC, 1978, 43, 2845
 
Name : HMBA-AM Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
0.9-1.2 mmol/g or as required
Usage : Preparation of cyclic peptides; peptide esters, etc.
Cleavage : Nucleophiles
References : R.C. Shephard etal, IJPPR, 1982, 20, 451
 
Name : HMBA-MBHA Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
0.9-1.2 mmol/g or as required
Usage : Preparation of cyclic peptides, peptide esters, etc.
Cleavage : Nucleophiles
Ref. S.M. Hutchins etal, TL, 1996, 37, 4869+C8
 
Name : 2-Chlorobenzhydrol resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Immobilisation of carboxylic acids
Cleavage : 30% TFA/DCM
References : K. Barlos etal, Ann, 1981, 951.
 
Name : Kaiser oxime resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Use : Syn. of carboxamides, hydrazides, hydroxamic acids
Cleavage : Anilines, hydrazines, hydroxylamine derrivatives
Ref.:W.F. Grado & E.T. Kaiser, JOC, 1980, 45, 1295; 1982, 47, 3258; ii) T. Sasaki etal, JOC, 1991, 56, 3159
 
Name : Rink acid resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Peptide synthesis for acids
Cleavage : 1% TFA-DCM
References : M. Nimizu etal, T, 1994, 50, 2691
 
Name : Rink acid resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
0.6 ± 0.2 mmol/g or as required
Usage : Peptide synthesis for acids
Cleavage : 1% TFA-DCM
References : H. Rink, TL, 1987, 28, 3787
 
Name : Knorr 2-CT Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
0.6 ± 0.2 mmol Fmoc/g or as required
Usage : Syn. of carboxamides by fragment condensation
Cleavage : Mild acids
Ref. T. Tselios, et al., J.Med. Chem., 1999, 42, 1170-77
 
Name : Rink Amide MBHA (Knorr) Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
0.6 ± 0.2 mmol Fmoc/g or as required
Usage : Syn. of carboxamides & sulfonamides
Cleavage : TFA
References :S. C. Story, IJPPR, 1992, 39, 87
 
Name : Rink Amide AM Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
0.6 ± 0.2 mmol Fmoc/g or as required
Usage : Syn. of carboxamides & sulfonamides
Cleavage : TFA
References :S. C. Story, IJPPR, 1992, 39, 87
 
Name : Sieber Amide Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Protected peptide amides
Cleavage : 1% TFA
References : i) P. Sieber, TL, 1987, 28, 2107.
 
Name : Sieber Ethylamide Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Preparation of peptide ethylamines
Cleavage : 1% TFA
References : W.C. Chan etal, JCS-CC, 1995, 1475
 
Name : Wang chloride resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Solid phase organic synthesis
Cleavage : TFA-DCM
References : W.C. Chan etal, JCS-CC, 1995, 1475
 
Name : Ramage Resin
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Peptide amides of terminal Phe, Tyr, Ile
Cleavage : 1% TFA
Ref. R. Ramage, et al., TL, 1993, 34, 6599
 
Name : Benzhydrylamine HCl PS
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Preparation of peptide amides by BOC stretagy
Cleavage : HF or TFMSA
References : G.R. Matsuede etal, Peptides, 1981, 2, 45
 
Name: Methylbenzhydrylamine HCl PS
Technical Information
1% cross-linked, 100-200 mesh; inquire for other specs.
1.0 ± 0.2 mmol/g or as required
Usage : Prepn of peptide amides, more acid labile than BHA
Cleavage : HF or TFMSA
References : G.R. Matsuede etal, Peptides, 1981, 2, 45
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